Cos-mic - Updated v1 Cos-Mic 2023 Schedule: A Galaxy of Entertainment Awaits! At Cos-Mic 2023, where the stars of entertainment align in a spectacular showcase! Secure Your Spot in …

 
d COSMIC cancer signature 6 (linked to MMR deficiency; left) is significantly similar to profiles from lung samples expressing low levels of MLH1 (right). The plot in the left panel represents the frequency of C>T mutations at the indicated tri-nucleotide context for signature 6. The plot in the right panel is the log ratio of C>T mutation rates …. Zoominfo log in

There's an issue and the page could not be loaded. Reload page. 9,824 Followers, 0 Following, 218 Posts - See Instagram photos and videos from Cos-mic (@cosmic_asia) Abstract. COSMIC, the Catalogue Of Somatic Mutations In Cancer ( https://cancer.sanger.ac.uk) is the most detailed and comprehensive resource for exploring the effect of somatic mutations in human cancer. The latest release, COSMIC v86 (August 2018), includes almost 6 million coding mutations across 1.4 million tumour samples, …COSMIC is currently the most comprehensive global resource for information on somatic mutations in human cancer, combining curation of the scientific literature with tumor resequencing data from the Cancer Genome Project at the Sanger Institute, U.K. Almost 4800 genes and 250000 tumors have been exa …The 20,000-light-year-long fountain of gas is moving at 450 times the top speed of a jet fighter. Comments (1) The galaxy NGC 4383 evolves as gas flows from its …We're excited to announce that Cos-Mic is back this year! Let’s dive into the world of games, anime, toys, cosplay, idols, and more. This year, we’re bringing even more incredible content, stunning exhibits, and experiences that will amaze you. 📅 September 14th, 15th, 16th, 2024 📍 Sunway Pyramid Convention Center Keep an eye out for more updates …Definition of cosmic adjective in Oxford Advanced Learner's Dictionary. Meaning, pronunciation, picture, example sentences, grammar, usage notes, synonyms and more.Whether you love gaming, music, anime, dressing up, or just exploring, Cos-Mic 2024 is the place to be. 📅 Mark Your Calendars: September 14th, 15th, 16th, 2024 📍 Where: Sunway Pyramid Convention Center Keep an eye out for more updates on our guest lineup, workshops, and special events that will make this year’s Cos-Mic …The gene view histogram is a graphical view of mutations across EZH2. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left.More details of the paper can be found by following the ‘COSMIC link’ or ‘Pubmed Link’. This table also provides the ability to search, sort and export the table in csv or tsv format. Reference Title - The abbreviated title of the article. Mouseover the title to see the full article title. Author – First author (s) of the publication, to see all authors of the publication …Import the ID field containing the stable COSMIC ID of each cancer-related mutation and the info field named ‘CNT’ that represents the number of cancer samples presenting this specific mutation.At Cos-Mic 2023, where the stars of entertainment align in a spectacular showcase! Secure Your Spot in the Stars: Tickets are flying fast! Grab yours and ensure your place in this interstellar celebration of talent and creativity. Stay Informed: Keep in mind, the universe is ever-changing, and so is our schedule.COSMIC v99, released 28-NOV-23. COSMIC, the Catalogue Of Somatic Mutations In Cancer, is the world's largest and most comprehensive resource for exploring the impact …Dec 6, 2023 · Published 5:22 PM EST, Wed December 6, 2023. Link Copied! McDonald's starts testing CosMc’s in Bolingbrook, Illinois this week. Courtesy McDonald's. New York CNN —. Shedding light on its long ... The Truth 2.0 out here https://blackhole.lnk.to/thetruth2Cosmic Gate have ticked another next-level livestream off their wish-list! After streaming sets from...The CMB is visible at a distance of 13.8 billion light years in all directions from Earth, leading scientists to determine that this is the true age of the Universe. However, it is not an ...The table shows the distribution of mutations across the primary tissue types that are curated by COSMIC. Histograms show the percentage of mutated samples for point mutations, CNV data and gene expression data. Moving your mouse over the histograms will show additional data. The number of samples tested on this page include samples …COSMIC Mutational Signatures version 3.4 is the latest release. Version 3 was released as part of COSMIC release v89 (May 2019), updated to version 3.1 in COSMIC release v91 (June 2020), to version 3.2 in COSMIC release v93 (March 2021), to version 3.3 in COSMIC v95 (May 2022) and most recently version 3.4 in COSMIC v98. …The spinoff restaurant is the latest nostalgia play by the chain and was first mentioned by McDonald's CEO Chris Kempczinski during the chain's second-quarter earnings call this summer. "CosMc's ...COSMIC Curated Genes & Fusions COSMIC contains curated somatic mutation data from the scientific literature, the Cancer Genome Project's systematic screens, and data from the ICGC and TCGA.. The first 3 tabs on this page summarise important cancer genes (curated and cancer census genes) and the 4th tab ('All genes') allows all COSMIC genes to be …Dec 6, 2023 · Published 5:22 PM EST, Wed December 6, 2023. Link Copied! McDonald's starts testing CosMc’s in Bolingbrook, Illinois this week. Courtesy McDonald's. New York CNN —. Shedding light on its long ... Apr 12, 2021 · What are cosmic rays? Cosmic rays are extremely high-energy subatomic particles – mostly protons and atomic nuclei accompanied by electromagnetic emissions – that move through space, eventually bombarding the Earth’s surface. They travel at nearly the speed of light, which is approximately 300 000 kilometres per second. Where do they come ... 👕 OFFICIAL XKITO MERCH STORE: https://dbh.la/xkito💚 Official xKito Music Spotify Playlist: https://spoti.fi/3c43dZN🎧 Buy/Stream: https://open.spotify.com/...The gene view histogram is a graphical view of mutations across ATM. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left.COSMIC is an online database of somatically acquired mutations found in human cancer. Somatic mutations are those that occur in non-germline cells that are not inherited by children. COSMIC, an acronym of Catalogue Of Somatic Mutations In Cancer, curates data from papers in the scientific literature and large scale experimental screens from the …CosMc's is a new spinoff restaurant idea from McDonald's.Kempczinski described it as "a small format concept with all the DNA of McDonald’s but its own …The one stop destination for all your gaming, computer accessories and audio requirements in India.Cosmic Unity 3. Better for your game, designed with sustainability in mind—two things you care about—the Cosmic Unity 3 has a secure, lightweight design for a low-to-the … Cosmic radiation is more intense in the upper atmosphere and most intense in deep space. The average annual dose or exposure from cosmic radiation is 0.33 mSv (33 mrem) or 11% of a person’s yearly exposure due to all natural sources of radiation. This yearly amount of radiation is similar to the amount of radiation from three chest x-rays. I'm very excited to announce a collaboration with Cos-Mic, a well-established pop culture event in Malaysia, along with Shikabashi, their official Live-2D …Apr 13, 2024 · cosmic. 1 (adjective) in the sense of extraterrestrial. Definition. occurring in or coming from outer space. Inside the heliosphere we are screened from cosmic rays. Synonyms. extraterrestrial. stellar. 2 (adjective) in the sense of universal. Abstract. COSMIC, the Catalogue Of Somatic Mutations In Cancer ( https://cancer.sanger.ac.uk) is the most detailed and comprehensive resource for exploring the effect of somatic mutations in human cancer. The latest release, COSMIC v86 (August 2018), includes almost 6 million coding mutations across 1.4 million tumour samples, … cosmic: 1 adj of or from or pertaining to or characteristic of the cosmos or universe “ cosmic laws” “ cosmic catastrophe” “ cosmic rays” adj inconceivably extended in space or time Synonyms: big , large above average in size or number or quantity or magnitude or extent COSMIC-3D integrates cancer mutations with protein structures across the human genome and structural proteome. Our unique combination of protein structure, mutation location/recurrence, and druggability predictions presents a vital tool for precision medicine, enabling high-resolution mutation-guided drug discovery. Get started now.These mutations are reported in the Catalogue of Somatic Mutations in Cancer (COSMIC). Structural appreciation of where these mutations appear, in protein-protein interfaces, active sites or deoxyribonucleic acid (DNA) interfaces, and predicting the impacts of these mutations using a variety of computational tools are crucial for … October 29 at 7:52 PM ·. Cos-Mic 2023 is coming to Sunway Pyramid Convention Center! Get ready, everyone! From 3rd to 5th November 2023, Sunway Pyramid Convention Center will transform into the epicenter of pop culture in Malaysia. Join the vibe as international artists take the stage for unforgettable performances. But that's not all! cosmic: 1 adj of or from or pertaining to or characteristic of the cosmos or universe “ cosmic laws” “ cosmic catastrophe” “ cosmic rays” adj inconceivably extended in space or time Synonyms: big , large above average in size or number or quantity or magnitude or extent Gene fusions. ABL1 is involved in 3 fusions, with the following genes: BCR (5483 mutations in 8847 samples) NUP214 (45 mutations in 873 samples) ETV6 (32 mutations in 811 samples) Drug sensitivity data. Mutations in ABL1 are associated with altered sensitivity to the following drug: Luminespib. See all drug sensitivity data for ABL1.Apr 16, 2024 · cosmic laws. 2. characteristic of the cosmos or its phenomena. cosmic events. 3. immeasurably extended in time and space; vast. 4. forming a part of the material universe, esp. outside of the earth. Also: cosmical SYNONYMS 3. immense, enormous, stupendous. The gene view histogram is a graphical view of mutations across ATM. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left.McDonald's has not announced what will be on the CosMc's menu. However, Chicago-area real estate investor Iman Jalali claims to have captured images of a menu board outside an upcoming CosMc's in ...Hey friends it's been a while again XD. I'm very excited to announce a collaboration with Cos-Mic, a well-established pop culture event in Malaysia, along wi...The table shows the distribution of mutations across the primary tissue types that are curated by COSMIC. Histograms show the percentage of mutated samples for point mutations, CNV data and gene expression data. Moving your mouse over the histograms will show additional data. The number of samples tested on this page include samples …Muat Turun Cos-Mic App dari App Store atau Google Play. Dafter; Pilih acara Cos-Mic 2023; Buat pembelian tiket; Lepas selesai buat pembelian, boleh dapatkan gelang di booth penebusan bertempat di Blue Atrium Sunway Pyramid pada hari kejadian dan penebusan boleh dilakukan bermula 31 Oktober sehingga 5 November! Untuk …Apr 5, 2024 · Cosmic microwave background (CMB), electromagnetic radiation filling the universe that is a residual effect of the big bang 13.8 billion years ago. Because the expanding universe has cooled since this primordial explosion, the background radiation is in the microwave region of the electromagnetic spectrum. Define cosmic. cosmic synonyms, cosmic pronunciation, cosmic translation, English dictionary definition of cosmic. also cos·mi·cal adj. 1. Of or relating to the regions of the universe distinct from Earth. COSMIC-3D integrates cancer mutations with protein structures across the human genome and structural proteome. Our unique combination of protein structure, mutation location/recurrence, and druggability predictions presents a vital tool for precision medicine, enabling high-resolution mutation-guided drug discovery. Get started now.The one stop destination for all your gaming, computer accessories and audio requirements in India.The gene view histogram is a graphical view of mutations across CDKN2A. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left.The table shows the distribution of mutations across the primary tissue types that are curated by COSMIC. Histograms show the percentage of mutated samples for point mutations, CNV data and gene expression data. Moving your mouse over the histograms will show additional data. The number of samples tested on this page include samples …b, Fraction of somatic SNVs detected in epithelial cells attributed to COSMIC signatures. SBS signatures associated with ultraviolet radiation (SBS7a, SBS7b, SBS7c and SBS7d) and clock-like ...Astronomers have spotted the largest cosmic explosion ever witnessed. The cosmic event, which occurred about 8 billion light-years from Earth, is 10 times brighter than any known exploding star.The gene view histogram is a graphical view of mutations across FGFR2. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left.At Cos-Mic 2023, where the stars of entertainment align in a spectacular showcase! Secure Your Spot in the Stars: Tickets are flying fast! Grab yours and ensure your place in this interstellar celebration of talent and creativity. Stay Informed: Keep in mind, the universe is ever-changing, and so is our schedule.The International Commission on Radiological Protection (ICRP) considers aircrew to be exposed to cosmic radiation on their jobs. They recommend effective dose limits of 20 mSv /year averaged over 5 years (that is, a total of 100 mSv in 5 years) for radiation workers and 1 mSv/year for the public. For pregnant radiation workers, the ICRP ...Within the last 4 years, COSMIC has substantially expanded its utility by adding new resources: the Mutational Signatures catalogue, the Cancer Mutation Census, and Actionability.Cosmic Manipulation. The Silver Surfer (Marvel Comics) possesses a fraction of the Power Cosmic, a source of ambient cosmic energy permeating the universe that makes possible the channeling and manipulation of energy. Power/Ability to: Control cosmic forces. "You may have some of the power of the saints, but you use it only for destruction.Tier 1 genes have documented evidence of their relevance to cancer. Curated gene. This is an expert curated gene . Mouse gene. Mouse insertional mutagenesis experiments support the designation of RB1 as a cancer causing gene. More information. Hallmark gene. This gene has a cancer hallmark . You can see more information about hallmarks.COS-MIC 2023 Malaysia. COS-MIC 2023 isn't just a pop culture event; it's a celebration of everything we love, cherish, and get excited about. From comics to movies, art, music, and beyond – if it's in pop culture, it's here. This epic event is happening from November 3 to 5, 2023 at the Sunway Pyramid Convention Center in Malaysia.cosmic X-ray background, X-ray radiation pervading the universe. In 1962 the first X-ray detectors were flown above Earth’s X-ray-absorbing atmosphere in a sounding rocket. In addition to discovering the first …Exciting News Alert! Jane, also known as Zhuā Yá (爪琊), is coming to Cos-Mic 2023 in Malaysia! Date: 3rd – 5th November 2023 Venue: Sunway Pyramid...osu! » beatmaps » Xomu - My Cos-Mic. Download osu! to create your own account!COSMIC comprises a number of subtly different data domains. Ninety percent of the mutation content adheres to the original goal of curating the world’s literature on known cancer genes. However, with the speed of DNA sequencing accelerate rapidly, tumour analysis is becoming less focused on single genes and it is not unusual to find …The table shows the distribution of mutations across the primary tissue types that are curated by COSMIC. Histograms show the percentage of mutated samples for point mutations, CNV data and gene expression data. Moving your mouse over the histograms will show additional data. The number of samples tested on this page include samples …1.0.7. Cos-Mic. Download APK (16 MB) Step into a world with Cos-Mic for an unique experience . Description Lifestyle. Advertisement.COSMIC, the "Catalogue Of Somatic Mutations In Cancer" is an expert-curated database encompassing the wide variety of somatic mutation mechanisms causing ... Wellcome Genome Campus, Hinxton, Cambridgeshire,Our high-resolution curation approach is globally unique, giving substantial insight into molecular biomarkers in human oncology. In addition, COSMIC also details more than six million noncoding mutations, 10,534 gene fusions, 61,299 genome rearrangements, 695,504 abnormal copy number segments and 60,119,787 abnormal expression variants.d COSMIC cancer signature 6 (linked to MMR deficiency; left) is significantly similar to profiles from lung samples expressing low levels of MLH1 (right). The plot in the left panel represents the frequency of C>T mutations at the indicated tri-nucleotide context for signature 6. The plot in the right panel is the log ratio of C>T mutation rates …‘COSMIC whole genomes’ displays only the genome-wide tumor analyses integrated into COSMIC, providing a view across the breadth of cancer genome data without any specific biases introduced via literature curation. ‘COSMIC’ displays all the data brought into the system across the project's life, including cell lines, whole genomes and …The cosmic microwave background (CMB) is a faint glow in microwave radiation that is almost perfectly uniform across the sky. This thermal radiation was emitted when the Universe became transparent to photons for the first time, when the Universe was about 400,000 years old. The CMB spectrum peaks at a wavelength of about 2 mm with a …CosMc's is a new spinoff restaurant idea from McDonald's.Kempczinski described it as "a small format concept with all the DNA of McDonald’s but its own …COS-MIC · 2024 the most awaited pop culture convention. Explore games, anime, toys, cosplay, idols, and more! This year, expect even more incredible content and stunning … Most related words/phrases with sentence examples define Cosmic meaning and usage. Thesaurus for Cosmic Related terms for cosmic - synonyms, antonyms and sentences with cosmic Quotes about cosmic . 1. The roles of art, morality, religion, political faith, science itself are not to repair organic exhaustion nor to provide sound functioning of the organs. All this supraphysical life is built and expanded not because of the demands of the cosmic environment but because of the demands of the social environment. - Emile ... The Truth 2.0 out here https://blackhole.lnk.to/thetruth2Cosmic Gate have ticked another next-level livestream off their wish-list! After streaming sets from...Import the ID field containing the stable COSMIC ID of each cancer-related mutation and the info field named ‘CNT’ that represents the number of cancer samples presenting this specific mutation.We're excited to announce that Cos-Mic is back this year! Let’s dive into the world of games, anime, toys, cosplay, idols, and more. This year, we’re bringing even more incredible content, stunning exhibits, and experiences that will amaze you. 📅 September 14th, 15th, 16th, 2024 📍 Sunway Pyramid Convention Center Keep an eye out for more updates …Buat peminat anime dan cosplay, jangan lepaskan peluang untuk menghadiri Cos-Mic 2023 di Sunway Pyramid Convention Center hujung minggu ini kerana pelbagai acara menarik menanti anda!. Konvensyen pop culture hebat ini menjanjikan pengalaman hebat untuk para pengunjung dengan pelbagai booth khas untuk peminat TACG (Toys, …CosMc's is a new spinoff restaurant idea from McDonald's.Kempczinski described it as "a small format concept with all the DNA of McDonald’s but its own …Date: 3rd – 5th November 2023. Venue: Sunway Pyramid Convention Centre. This is YOUR chance to meet and mingle with Jane! Don't miss out on an unforgettable …Introducing PHI, our dazzling 6 out of 6 Cos-Mic Stars, in a special showcase video that intertwines her enchanting talents with the transformative power of M∙A∙C Cosmetics! From spellbinding looks to celestial performances, prepare to embark on a journey that transcends time and space, only at Cos-Mic 2023 from November 3rd …The gene view histogram is a graphical view of mutations across CALR. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left.The gene view histogram is a graphical view of mutations across ACVR2A. These mutations are displayed at the amino acid level across the full length of the gene by default. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. Synonyms for COSMIC: catholic, cosmopolitan, global, planetary, universal, ecumenical, pandemic, huge, immense, infinite, limitless, worldwide, vast, vast, empyrean ... At CosMc’s, we take great care to serve quality, great-tasting menu items to our customers each and every time they visit our restaurants. We understand that each of our … Cosmic definition: of or relating to the cosmos. See examples of COSMIC used in a sentence. shipping policy shipping/fulfulment policy This policy outlines the terms and conditions relating to the delivery and fulfilment of goods and services from us and/or the third-party suppliers/providers to you. Your usage of our Application shall be deemed as your acknowledgment and agreement to the terms of this policy. Shipment availability We, …

This event will take place at Sunway Clio Exhibition Centre and will be held from 24th to 26th June from 10 am – 7 pm. Our Cos-mic event gives an opportunity for Doujin related to Anime, Artwork and Cosplayers to showcase their newest products or arts and illustrations. For the attendees of the event, it obviously will give thousands of .... Grocery calculator

cos-mic

At Cos-Mic 2023, where the stars of entertainment align in a spectacular showcase! Secure Your Spot in the Stars: Tickets are flying fast! Grab yours and ensure your place in this interstellar celebration of talent and creativity. Stay Informed: Keep in mind, the universe is ever-changing, and so is our schedule.COS-MIC · 2024 the most awaited pop culture convention. Explore games, anime, toys, cosplay, idols, and more! This year, expect even more incredible content and stunning …If you use COSMIC in your work, please cite our most recent article in any publications ( Sondka et al., 2023 ). COSMIC: a curated database of somatic variants and clinical data for cancer (Sondka et al., 2023) COSMIC: the Catalogue of Somatic Mutations in Cancer (Tate et al., 2018) The COSMIC Cancer Gene Census: describing genetic dysfunction ...Introducing PHI, our dazzling 6 out of 6 Cos-Mic Stars, in a special showcase video that intertwines her enchanting talents with the transformative power of M∙A∙C Cosmetics! From spellbinding looks to celestial performances, prepare to embark on a journey that transcends time and space, only at Cos-Mic 2023 from November 3rd …Cosmology is the study of the universe; its birth, evolution, and ultimate fate. This includes further developing and refining the prevailing model, the Big Bang theory, investigating the universe ...shipping policy shipping/fulfulment policy This policy outlines the terms and conditions relating to the delivery and fulfilment of goods and services from us and/or the third-party suppliers/providers to you. Your usage of our Application shall be deemed as your acknowledgment and agreement to the terms of this policy. Shipment availability We, …Now encompassing the majority of molecular mutation mechanisms in oncogenetics, COSMIC additionally describes 10 million non-coding mutations, 1 million copy-number aberrations, 9 million gene-expression variants, and almost 8 million differentially methylated CpGs. This information combines a consistent interpretation of …COSMIC Mutational Signatures version 3.4 is the latest release. Version 3 was released as part of COSMIC release v89 (May 2019), updated to version 3.1 in COSMIC release v91 (June 2020), to version 3.2 in COSMIC release v93 (March 2021), to version 3.3 in COSMIC v95 (May 2022) and most recently version 3.4 in COSMIC v98. …Tier 1 genes have documented evidence of their relevance to cancer. Curated gene. This is an expert curated gene . Mouse gene. Mouse insertional mutagenesis experiments support the designation of RB1 as a cancer causing gene. More information. Hallmark gene. This gene has a cancer hallmark . You can see more information about hallmarks.Physical cosmology is the study of the observable universe 's origin, its large-scale structures and dynamics, and the ultimate fate of the universe, including the laws of science that govern these areas. [4] It is investigated by scientists, including astronomers and physicists, as well as philosophers, such as metaphysicians, philosophers of ...This event will take place at Sunway Clio Exhibition Centre and will be held from 24th to 26th June from 10 am – 7 pm. Our Cos-mic event gives an opportunity for Doujin related to Anime, Artwork and Cosplayers to showcase their newest products or arts and illustrations. For the attendees of the event, it obviously will give thousands of ...Apr 11, 2022 · Figure 29.4.1 29.4. 1 Cosmic Microwave Background and Clouds Compared. (a) Early in the universe, photons (electromagnetic energy) were scattering off the crowded, hot, charged particles and could not get very far without colliding with another particle. But after electrons and photons settled into neutral atoms, there was far less scattering ... Cosmic rays ionize nitrogen and oxygen molecules in the atmosphere, which leads to a number of chemical reactions. Cosmic rays are also responsible for the continuous production of a number of unstable isotopes, such as carbon-14, in the Earth's atmosphere through the reaction: n + 14 N → p + 14 C. Cos-Mic 2023 is coming to Sunway Pyramid Convention Center! Get ready, everyone! From 3rd to 5th November 2023, Sunway Pyramid Convention Center will transform into the epicenter of pop culture in Malaysia. Join the vibe as international artists take the stage for unforgettable performances. But that's not all!Cos-Mic Annoucement The moment you have been waiting for is finally here!! And here is our ticketing announcement! We want to make things easy for...If you use COSMIC in your work, please cite our most recent article in any publications ( Sondka et al., 2023 ). COSMIC: a curated database of somatic variants and clinical data for cancer (Sondka et al., 2023) COSMIC: the Catalogue of Somatic Mutations in Cancer (Tate et al., 2018) The COSMIC Cancer Gene Census: describing genetic dysfunction ...The 20,000-light-year-long fountain of gas is moving at 450 times the top speed of a jet fighter. Comments (1) The galaxy NGC 4383 evolves as gas flows from its ….

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